ABSTRACT
Background: The main objective of this study was to evaluate prescription patterns of antihypertensives in preeclampsia patients at a tertiary care hospital in Central India.Methods: The study belongs to retrospective observational type. he study was conducted by department of Pharmacology in association of department of Obstetrics & Gynaecology department at Nkp Salve Institute of Medical Sciences & Research Centre, Lata Mangeshkar Hospital, Nagpur. Permission from Institute Ethics Committee was taken for studying the prescribing patterns of drugs. The study was conducted for a period of 6 months. Inclusion and Exclusion criteria were added.Results: The maximum number patients seen in age groups 36-41 (28.6%). The main drug prescribed in our study was Labetalol followed by methyldopa. In our study most of the patients were of moderate and mild type corresponding to 48% and 32% respectively and only 20% of patients belong to severe cases. In our study highest number of patients was seen in second gravida i.e. 33.33%.Conclusions: Labetalol was the most common anti hypertensive prescribed in pre eclampsia patients. Rationale prescribing of drugs were done.
ABSTRACT
Background: Musculoskeletal disorders like osteoarthritis, rheumatoid arthritis, bursitis, backache, tendinitis, cervical spondylitis etc. are very commonly encountered in orthopaedic practice and are generally treated with various analgesic drugs. There are number of non-steroidal anti-inflammatory drugs (NSAIDs), opiod analgesics and also fixed dose combination (FDC) of analgesics available for the treatment of such disorders with some advantages and disadvantages of these drugs. Since few studies are there on utilization of analgesic drugs in the orthopaedic practice, this study was undertaken to determine the current prescribing trends for these disorders.Methods: It was record based observational study carried out at NKP salve institute of medical sciences, Nagpur. A total of 200 prescriptions of patients reported to orthopaedic outpatient department, with presenting complaints of musculoskeletal disorder and rheumatological conditions like osteoarthritis, rheumatoid arthritis, bursitis, backache, tendinitis, cervical spondylitis etc. were noted for the various analgesic drugs prescribed for these disorders.Results: The common age groups encountered for musculoskeletal disorders were between 41-50 years (26%) and 31-40 years (20%) followed by other age groups. The common conditions for which patient attended orthopaedic outpatient department were low backpain in 42 (21%) and osteoarthritis in 41(20.5%) patients followed by others. Aceclofenac and diclofenac were the most commonly prescribed analgesics in 25 (12.5%) and18 (9%) patients followed by other analgesics. Fixed dose combinations of NSAIDS with other NSAIDS or opoid analgesic were also commonly prescribed. Diclofenac + Paracetamol and Tramadol + Paracetamol were most commonly prescribed combinations in 30 (15%) and 19 (9.5%) patients respectively.Conclusions: As monotherapy aceclofenac and diclofenac were the most commonly prescribed NSAIDS for various musculoskeletal disorders. Also, fixed dose combinations of NSAIDS with other NSAIDS or opoid analgesic were also commonly prescribed. Diclofenac + Paracetamol and Tramadol + Paracetamol were the most commonly prescribed FDCs in our study.